DNA Risk: HLA-Related Autoimmunity looks at gene variants related to common autoimmune diseases and provides healthcare practitioners ‘diagnostic insight’ for patients already suffering from an autoimmune disorder, or who are identified as at-risk due to a family history of disease and exposure to environmental risk factors. This test analyses thousands of gene variants within the MHC and HLA gene region to report on HLA types, specific to HLA class I (HLA-A, -B, -C), and HLA class II (HLA-DPA1, -DPB1, -DQA1, -DQB1, -DRB1, -DRB3, -DRB4, and -DRB5) loci, and MHC related gene variants associated with common autoimmune diseases.
THE AUTOIMMUNE DISEASES DISCUSSED IN THIS REPORT INCLUDE:
• Alopecia areata (AA)
• Ankylosing spondylitis (AS)
• Coeliac disease (CD)
• Graves’ disease (GD)
• Hashimoto thyroiditis (HT)
• Idiopathic membranous nephropathy (IMN)
• IgA nephropathy (IgAN)
• Lyme borreliosis
• Multiple sclerosis (MS)
• Rheumatoid arthritis (RA)
• Systemic lupus erythematosus (SLE)
• Vitiligo