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This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.

Elispot looks at the T cell response and IGG/IGM looks at B cells/Antibodies. 

Some people don't produce antibodies and have a more active T cell response. 

In an ideal world to assess an infection, a practitioner should look at both sides of the immune system response, in other words, Eli-spot for the T cells/cellular response and IGG/IGM for humoral/B cell/antibody response.

To check for an active infection with the T cells, the Elispot is recommended.

Yersinia is a genus of bacteria in the family Yersiniaceae. Its species are Gram-negative, coccobacilli bacteria, a few micrometers long and fractions of a micrometer in diameter, and are facultative anaerobic. Some members of Yersinia are pathogenic in humans, such as Yersinia enterocolitica, Yersinia pseudotuberculosis and Yersinia pestis. Rodents are the natural reservoirs of Yersinia, less frequently, other mammals serve as hosts. Yersinia species are further found in soil and waters.

Infection may occur either through blood (in the case of Y. pestis) or in an alimentary fashion, occasionally via consumption of food products (especially vegetables, milk-derived products, and meat) contaminated with infected urine or feces.

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