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The Epstein-Barr Virus Elispot-LTT test is designed to detect the Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), which is of the herpes family, and is one of the most common viruses in humans.

The Epstein-Barr virus is best known as the cause of infectious mononucleosis (glandular fever). However, it s also associate with particular forms of cancer, such as Hodgkin’s lymphoma, Burkitt’s lymphoma, nasopharyngeal carcinoma, and central nervous system lymphomas, associated with HIV.

Elispot-LTT tests:

The result of the EliSpot test indicates current celluar activity against Epstein-Barr-Virus (EBV).  

  • EBV-lytic antigen: sign for replication of infectious EBV virions 
  • EBV-latent antigen: sign for EBV latency with no production of infectious EBV virions


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